In Africa, the challenges of the past few years— including the ongoing impacts of the Russian-Ukraine conflict, the COVID-19 pandemic, supply chain disruptions, conflict, and global environmental change are reversing decades of progress and exacerbating food insecurity and malnutrition. The Africa Agriculture Status Report (AASR) 2022 provides evidence and insights on the prospects of accelerating the transformation of Africa’s food systems toward resilience and sustainability, anchored in the 2021 United Nations Food Systems Summit (UNFSS).